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Each 50 mg/12.5 mg film-coated tablet contains losartan potassium 50 mg and hydrochlorothiazide 12.5 mg while 100 mg/25 mg film-coated tablets contains losartan potassium 100 mg and hydrocholorothiazide 25 mg.
Losartan potassium is 2-butyl-4-chloro-1-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]imidozole-5-methanol potassium and hydrochlorothiazide is 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulphonamide 1,1-dioxide.
Losartan potassium has a molecular weight of 461 and an empirical formula of C22H22ClKN6OK while hydrochlorothiazide has a molecular weight of 297.7 and an empirical formula of C7H8ClN3O4S2.
